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Clinical trials for Hypoxic Hypoxia

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    The EU Clinical Trials Register currently displays   43893   clinical trials with a EudraCT protocol, of which   7300   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    31 result(s) found for: Hypoxic Hypoxia. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2008-005985-30 Sponsor Protocol Number: rosucaf2 Start Date*: 2009-01-22
    Sponsor Name:Department of Pharmacology-Toxicology
    Full Title: Is augmentation of PORH by rosuvastatin adenosine-receptor mediated?
    Medical condition: mechanism of influence of statins on human adaptive mechanisms in hypoxic circumstances
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021143 Hypoxia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002251-33 Sponsor Protocol Number: 01 Start Date*: 2006-10-10
    Sponsor Name:University of Vienna
    Full Title: Hypoxia Imaging with the novel Radiopharmaceutical 18F Fluoroazomycin Arabinoside (FAZA)- Prognostic impact in Cervical Cancer .
    Medical condition: Twenty-five patients with cervical carcinoma (T2Nx or TxN1) will be included in the present study. In addition to the routine pre-therapeutical staging of cervical cancer, 18FAZA PET will be perfor...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2015-005222-19 Sponsor Protocol Number: BREATH Start Date*: 2016-07-14
    Sponsor Name:Leiden University Medical Center
    Full Title: Effect of neuromuscular blockade and reversal by sugammadex versus neostigmine on breathing when hypoxic or hypercapnic in volunteers
    Medical condition: Postoperative ventilatory control
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004855 10038680 Respiratory depression postoper LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-003363-25 Sponsor Protocol Number: NA Start Date*: 2020-08-18
    Sponsor Name:Department of Intensive Care, Rigshospitalet
    Full Title: Higher vs. Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia: the COVID STEROID 2 trial
    Medical condition: Adult patients with COVID-19 and severe hypoxia.
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004862 10084401 COVID-19 respiratory infection LLT
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10021143 Hypoxia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-021139-15 Sponsor Protocol Number: ESC-928-MOL-0000-I Start Date*: Information not available in EudraCT
    Sponsor Name:Technische Universität München Fakultät für Medizin
    Full Title: Do Selective Radiation Dose Escalation and Tumor Hypoxia Status Impact the Locoregional Tumor Control after Radiochemotherapy of Head & Neck Tumors?
    Medical condition: This study tests the hypothesis that the Radiation dose escalation to the macroscopic Tumor improves the locoregional control survival after concomitant chemoradiation over 2 years. As a transla...
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10067821 Head and neck cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004133-27 Sponsor Protocol Number: DAHANCA30 Start Date*: 2016-04-18
    Sponsor Name:Århus Universitetshospital Afd for Eksp. Klinisk onkologi
    Full Title: A randomized non-inferiority trial of hypoxia-profile guided hypoxic modification with nimorazole during radiotherapy/chemoradiotherapy of squamous cell carcinoma of the head and neck
    Medical condition: Patients with squamous cell carcinoma of the head and neck
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003621-41 Sponsor Protocol Number: DESIRED Start Date*: 2016-12-05
    Sponsor Name:Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital
    Full Title: Desferal administration to improve the impaired reaction to hypoxia in diabetes (DESIRED) A randomised, double-blind, placebo-controlled, cross-over study
    Medical condition: The study will investigate the effect of deferoxamine on the impaired reaction to hypoxia in patients with diabetes mellitus type 1.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003063-12 Sponsor Protocol Number: NEU-01-02-1A Start Date*: 2016-09-14
    Sponsor Name:Neurophyxia B.V.
    Full Title: TIBC study: A multiple-centre Phase 2 trial comparing the efficacy of 2-Iminobiotin (2-IB) treatment to standard care in neonates with gestational age of ≥36 weeks with moderate to severe perinatal...
    Medical condition: Perinatal asphyxia
    Disease: Version SOC Term Classification Code Term Level
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10003500 Asphyxia neonatal LLT
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10028923 Neonatal asphyxia PT
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10004943 Birth asphyxia LLT
    19.0 100000004868 10028946 Neonatal hypoxia and asphyxia HLT
    19.0 100000004852 10021147 Hypoxic encephalopathy LLT
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10022820 Intrauterine hypoxia and birth asphyxia LLT
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10040441 Severe birth asphyxia LLT
    19.0 100000004852 10070512 Hypoxic-ischemic encephalopathy LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2020-000057-27 Sponsor Protocol Number: 72544 Start Date*: 2021-10-27
    Sponsor Name:Leiden University Medical Center
    Full Title: Recovery of carotid body function after full recovery neuromuscular block
    Medical condition: Postoperative ventilatory control
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001375-32 Sponsor Protocol Number: PreToVid Start Date*: 2020-04-03
    Sponsor Name:UMCG
    Full Title: Pre-emptive tocilizumab in hypoxic COVID-19 patients, a prospective randomized trial
    Medical condition: Hypoxia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2015-005278-40 Sponsor Protocol Number: ABR-55752 Start Date*: 2016-11-29
    Sponsor Name:Radboudumc
    Full Title: Molecular imaging before and during (chemo-) radiotherapy in patients with locally advanced Head and Neck, thoracic and pelvic tumors: prognostic and predictive value of 18F-fluoroazomycin arabinos...
    Medical condition: Head and neck squamous cell carcinoma (HNSCC)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060121 Squamous cell carcinoma of head and neck PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004119-36 Sponsor Protocol Number: METOXY-LACC Start Date*: 2019-11-04
    Sponsor Name:Oslo University Hospital
    Full Title: Altered tumor oxygenation by Metformin, a potential step in overcoming radiotherapy resistance in locally advanced cervical cancer.
    Medical condition: Locally advanced cervical cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10008229 Cervical cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002441-12 Sponsor Protocol Number: 1219 Start Date*: 2013-12-16
    Sponsor Name:European Organisation for Research and Treatment of Cancer
    Full Title: A blind randomized multicenter study of accelerated fractionated chemo-radiotherapy with or without the hypoxic radiosensitizer nimorazole (Nimoral), using a 15 gene signature for hypoxia in the tr...
    Medical condition: Squamous cell carcinoma of the head and neck
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060121 Squamous cell carcinoma of head and neck PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) NL (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2012-005812-24 Sponsor Protocol Number: MalinJonssonFagerlund10 Start Date*: 2013-05-02
    Sponsor Name:Karolinska University Hospital
    Full Title: Acute ventilatory response to hypoxia during sedation with dexmedetomidine compared to propofol in healthy volunteers.
    Medical condition: Healthy volunteers and the acute hypoxic ventilatory response during sedation with dexmedetomidine compared to propofol.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10068084 Anesthesia procedure LLT
    14.1 100000004865 10062825 Monitored anaesthesia care sedation LLT
    Population Age: Adults Gender: Male
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000528-17 Sponsor Protocol Number: IAEA-HypoX Start Date*: 2012-06-05
    Sponsor Name:Department of Experimental Clinical Oncology
    Full Title: A randomized multicenter study of accelerated fractionated radiotherapy with or without the hypoxic radiosensitizer nimorazole in the treatment of squamous cell carcinoma of the head and neck
    Medical condition: Squamous Cell Carcinoma of the Head and Neck region
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SI (Ongoing) EE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005796-18 Sponsor Protocol Number: 03-217 Start Date*: 2009-07-21
    Sponsor Name:WKZ / UMC Utrecht
    Full Title: Does antenatal allopurinol during asphyxia reduce post-hypoxic-ischemic reperfusion damage in the newborn?
    Medical condition: Perinatal asphyxia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004943 Birth asphyxia LLT
    9.1 10014633 Encephalopathy neonatal LLT
    Population Age: In utero, Preterm newborn infants, Newborns, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000936-17 Sponsor Protocol Number: GWEP1560 Start Date*: 2019-07-23
    Sponsor Name:GW Research Ltd
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Single-Ascending Dose Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of GWP42003-P in Conjunction with Hypothermia in Neonates with ...
    Medical condition: Neonatal Hypoxic-Ischemic Encephalopathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10070512 Hypoxic-ischemic encephalopathy LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10050081 Neonatal hypoxia PT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) ES (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2016-000497-38 Sponsor Protocol Number: DEX-PCH-VMNI Start Date*: 2016-08-23
    Sponsor Name:Ana Vallejo De la Cueva
    Full Title: Dexmedetomidine versus current clinical practice for non-invasive mechanical ventilation: a randomized clinical trial
    Medical condition: Accute respiratory insuffienciency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000377-12 Sponsor Protocol Number: CHUBX2014/26 Start Date*: 2017-09-18
    Sponsor Name:CHU de Bordeaux
    Full Title: MISOBOLD - Prostate cancer hypoxia using BOLD MRI and 18F-FMISO PET imaging
    Medical condition: Prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036909 Prostate cancer metastatic PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029104 Neoplasms benign, malignant and unspecified (incl cysts and polyps) SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001008-23 Sponsor Protocol Number: RIOP-1 Start Date*: 2014-09-26
    Sponsor Name:The Newcastle Upon Tyne Hospital NHS Foundation Trust, Freeman Hospital
    Full Title: Riociguat in patients with respiratory disease and hypoxia – a proof-of-concept study
    Medical condition: Pulmonary hypertension WHO Group III (Pulmonary hypertension owing to lung disease and/or hypoxia): Chronic obstructive pulmonary disease(COPD); Pulmonary Fibrosis (PF).
    Disease: Version SOC Term Classification Code Term Level
    18.1 10038738 - Respiratory, thoracic and mediastinal disorders 10037400 Pulmonary hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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